Matt Barrows of The Athletic reported that he expects the 49ers to be in the mix to draft a running back in the NFL Draft. (Source: Matt Barrows)

Fantasy Impact: This was likely as soon as San Francisco recently traded Jordan Mason to the Vikings. Guerendo remains the backup to Christian McCaffrey for now, but that could change depending on who it is the 49ers draft.

The 49ers released C/LS Taybor Pepper. (Source: Aaron Wilson on Twitter)

Fantasy Impact: Pepper struggled last season heading into what was going to be his contract year next season. He'll look to land a role with another team.

The 49ers signed QB Mac Jones to a two-year, $7 million contract. (Source: Ian Rapoport on Twitter)

Fantasy Impact: San Francisco reportedly had interest in Jones when it drafted Trey Lance back in 2021. The deal includes $5 million guaranteed and a maximum value of $11.5 million. He'll provide insurance for the 49ers behind Brock Purdy.

The 49ers signed S Jason Pinnock to a one-year deal. (Source: Aaron Wilson on Twitter)

Fantasy Impact: Pinnock heads to the west coast after spending last season with the Giants where he recorded three sacks and two interceptions. He'll add depth in the secondary for San Francisco.

The 49ers agreed to terms with LB Luke Gifford to a one-year contract. (Source: Matt Barrows on Twitter)

Fantasy Impact: Gifford will add depth in the linebacker room for a 49ers defense that has lost a number of pieces already this offseason.

The 49ers signed LB Curtis Robinson to a one-year deal. (Source: Matt Barrows on Twitter)

Fantasy Impact: San Francisco re-signed Robinson on a one-year deal instead of tendering him. He is continuing to work his way back from a torn ACL he suffered back in September.

The 49ers released LB Leonard Floyd. (Source: Adam Schefter on Twitter)

Fantasy Impact: In his lone season in San Francisco last year, Floyd logged 8.5 sacks with one forced fumble. He should have no problem finding another landing spot as a free agent.

The 49ers have tendered RB Jordan Mason with the second-round tender. (Source: Adam Schefter on Twitter )

Fantasy Impact: Mason is now a restricted free agent, meaning the 49ers will have a chance to match any offer Mason receives from another team. He tallied 789 rushing yards and three touchdowns in 12 games with the 49ers last season.

The 49ers signed TE Luke Farrell to a three-year contract. (Source: Ian Rapoport on Twitter)

Fantasy Impact: Farrell will get $11 million guaranteed as part of the deal. He'll add depth in the 49ers tight end room behind George Kittle.

The 49ers signed RB Patrick Taylor to a one-year contract extension. (Source: Adam Schefter on Twitter)

Fantasy Impact: Taylor saw 39 carries last season. He'll remain in primarily a special teams role with the 49ers.

Former San Francisco 49ers running back Elijah Mitchell is signing a one-year deal with the Kansas City Chiefs. (Source: Tom Pelissero on Twitter)

Fantasy Impact: While Isiah Pacheco dealt with injury in 2024 and struggled to return to form, the next option in K.C. was bringing in Kareem Hunt. Looking ahead to 2025, the Chiefs are building in new insurance plans, bringing in a back who has proven to be an efficient runner when given the chance. However, Mitchell comes with his own injury history, including a season-ending injury in 2024 (hamstring), an MCL sprain in 2022, and multiple others. The deal is worth $3.5 million, per Fox Sports' Jordan Schultz.

The 49ers claimed CB Tre Tomlinson off waivers from the Rams.

Fantasy Impact: Tomlinson was released by the Rams earlier this week. He lands a fresh start in San Francisco.

The San Francisco 49ers plan to release DT Javon Hargrave at the start of the league's new year, setting him up to be a free agent. (Source: Adam Schefter on Twitter)

Fantasy Impact: Hargrave joins a free agent DT class that has players who could be impactful but don't have name brands, so while Hargrave struggled with injury in 2024 (career-low defensive grade of 60.6 before triceps tear), he could certainly catch attention given his past performance (three straight seasons of 7.5+ sacks).

Deebo Samuel Sr. has been traded to the Washington Commanders in exchange for a fifth-round draft pick. (Source: Ian Rapoport on Twitter)

Fantasy Impact: It was previously reported that several teams were pursuing a trade for Samuel, and now the Commanders are able to get a deal done with the 49ers to acquire the veteran wideout. They are sending a fifth-round pick to San Francisco in exchange for him, and this deal will be good for QB Jayden Daniels coming off of a Rookie of the Year campaign in his first season at the helm for Washington. This is less than ideal for the fantasy value of Terry McLaurin, but there should be enough to go around on this offense to support both of them in the 2025-2026 NFL season.

49ers GM John Lynch said he expects Christian McCaffrey to be ready for at least parts of the offseason program. (Source: Matt Barrows on Twitter)

Fantasy Impact: Lynch said McCaffrey is “doing great, doing really well.” CMC said back in January that he was close to being fully healthy. He should be good to go by training camp.

49ers GM John Lynch said team and TE George Kittle's reps have had some talks on an extension. (Source: Nick Wagoner on Twitter)

Fantasy Impact: Lynch added that the team wants Kittle to retire a 49er. The team has other deals and extension to focus on this offseason, but it appears both sides are interested in an extension. "That's something we all want to see become a reality," Lynch said.

49ers GM John Lynch says talks have been on going with LB Dre Greenlaw. (Source: Nick Wagoner on Twitter)

Fantasy Impact: The 49ers are hoping that a deal can be struck before free agency, though Greenlaw may test the market first. "Hopefully we come to agreement," Lynch said. "We've been having (negotiations), so we'll see if we can progress it."

49ers GM John Lynch said Brandon Aiyuk's ACL recovery has gone well so far. (Source: Matt Barrows on Twitter)

Fantasy Impact: "The real top-end athletes tend to heal at a little faster rate, and I think that’s going on with Brandon as well," Lynch said. Aiyuk's status for the start of the 2025 season remains uncertain, but he does appear to be progressing. With Deebo Samuel requesting a trade, San Francisco will likely look to bring in a wide receiver or two this offseason.

49ers GM John Lynch said they have started contract negotiations with Brock Purdy. (Source: Clayton Holloway on Twitter)

Fantasy Impact: This has been the expectation all offseason as Purdy was expected to reach an agreement on a contract extension. The question will be how much he gets per year in the deal. It is a matter of when, not if an extension happens.

49ers GM John Lynch shared Wednesday at the 2025 NFL Scouting Combine that Trent Williams (ankle) is “motivated” to play a 16th NFL season and will stay with San Francisco. The 36-year-old left tackle, a cornerstone of the line, held strong as an elite performer in 2024 when healthy, though a left ankle injury sidelined him for the final seven games, limiting him to 10 starts. Williams is on the mend from that injury, with Lynch signaling confidence in his return as the team’s starting left tackle in 2025.

Fantasy Impact: Williams’ return is a quiet win for fantasy managers rostering 49ers skill players—think Brock Purdy, Christian McCaffrey, or George Kittle. His top-tier blocking keeps the offense humming, though last year’s 10-game stint highlights durability concerns at 36. The ankle recovery bears watching, but a full offseason should have him ready to anchor the line. No direct fantasy value at tackle, but his presence boosts Purdy’s protection and McCaffrey’s lanes—keep those guys high on your draft board.