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Isaac Guerendo

Isaac Guerendo

RB - San Francisco 49ers

Height: 6' Weight: 221 lbsAge: 25College: Louisville

Week 15 Outlook

TEN @ SF
Sun 4:25pm ET
54°
Matchup (?)
Week Rank (ECR) RB #93
Projection 0.9 pts

Roster %

 
Yahoo
2%
 
ESPN
2%
 
FanDuel
 
DraftKings

Availability



Player News
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Isaac Guerendo (shoulder) will play Sunday

Isaac Guerendo (shoulder) will play in Sunday's game against the Seattle Seahawks.

Fantasy Impact

The young running back was able to practice fully all week despite being listed on the injury report with a shoulder issue. He will be good to go for Week 1 and will be primed for an increase in touches if Christian McCaffrey (calf) is ruled out ahead of game time for the 49ers.

Leo Sells14 weeks ago
Recent Articles
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Fantasy Football Week 15 Rankings, Grades & Start/Sit Advice (2025) photo

Welcome to Week 15, and welcome to Quick Grades, your weekly companion for start/sit clarity. We’ve combined consensus rankings and projections with The Primer’s matchup analysis to assign letter grades for every fantasy-relevant player, then added concise notes to illuminate … read more »

Image of FantasyPros Staff by FantasyPros Staff in FantasyDec 14, 2025
Rankings
ECRBestWorst# of Experts
Week 15RB #93RB #84RB #10412
Rest of Season RB #73RB #68RB #835
Dynasty RB #65RB #65RB #754
Projections
(Week 15)
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Projections (Week 15)
Rush AttRush YdsRush TdsRecsRec YdsRec TdsFumblesPoints
14.900.11000.9
History
Statistics
(avgs.)
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Statistics (avgs.)
Rush YdsRush TdsRecsPoints
Last Week0000
Last 3 Weeks0000
Season to Date0000
Game Log
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Game Log
OPPRush YdsRush TdsRecsPoints
Week 13@ CLE0000
Week 11@ ARI0000
Week 9@ NYG0000
Week 7vs. ATL0000
Strength of Schedule
(2025)
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Strength of Schedule (2025)
OppSummary
Next Gamevs. TEN11th easiest opponent
Next 3 GamesIND, CHI, SEA26th easiest opponents
Playoffs (?)TEN, IND, CHI19th easiest opponents
Rest of Season--19th easiest remaining opponents