Isaac Guerendo
RB - San Francisco 49ers
Height: 6' Weight: 221 lbsAge: 25College: Louisville
54°Availability
Player News
View More NewsIsaac Guerendo (shoulder) will play Sunday
Isaac Guerendo (shoulder) will play in Sunday's game against the Seattle Seahawks.
Fantasy Impact
The young running back was able to practice fully all week despite being listed on the injury report with a shoulder issue. He will be good to go for Week 1 and will be primed for an increase in touches if Christian McCaffrey (calf) is ruled out ahead of game time for the 49ers.
Recent Articles
View More Articles | Welcome to Week 15, and welcome to Quick Grades, your weekly companion for start/sit clarity. We’ve combined consensus rankings and projections with The Primer’s matchup analysis to assign letter grades for every fantasy-relevant player, then added concise notes to illuminate … read more »  by in FantasyDec 14, 2025 |
Rankings
View More Rankings| ECR | Best | Worst | # of Experts | |
|---|---|---|---|---|
| Week 15 | RB #93 | RB #84 | RB #104 | 12 |
| Rest of Season | RB #73 | RB #68 | RB #83 | 5 |
| Dynasty | RB #65 | RB #65 | RB #75 | 4 |
| Rush Att | Rush Yds | Rush Tds | Recs | Rec Yds | Rec Tds | Fumbles | Points |
|---|---|---|---|---|---|---|---|
| 1 | 4.9 | 0 | 0.1 | 1 | 0 | 0 | 0.9 |
History
| Rush Yds | Rush Tds | Recs | Points | |
|---|---|---|---|---|
| Last Week | 0 | 0 | 0 | 0 |
| Last 3 Weeks | 0 | 0 | 0 | 0 |
| Season to Date | 0 | 0 | 0 | 0 |
Game Log
View More Games| OPP | Rush Yds | Rush Tds | Recs | Points | |
|---|---|---|---|---|---|
| Week 13 | @ CLE | 0 | 0 | 0 | 0 |
| Week 11 | @ ARI | 0 | 0 | 0 | 0 |
| Week 9 | @ NYG | 0 | 0 | 0 | 0 |
| Week 7 | vs. ATL | 0 | 0 | 0 | 0 |
| Opp | Summary | |
|---|---|---|
| Next Game | vs. TEN | 11th easiest opponent |
| Next 3 Games | IND, CHI, SEA | 26th easiest opponents |
| Playoffs (?) | TEN, IND, CHI | 19th easiest opponents |
| Rest of Season | -- | 19th easiest remaining opponents |
