| Week 1 | Pittsburgh Steelers vs. Atlanta Falcons | Sunday, September 8th, 2024 at 1:00pm ET |
| Week 2 | Pittsburgh Steelers vs. Denver Broncos | Sunday, September 15th, 2024 at 4:25pm ET |
| Week 3 | Los Angeles Chargers vs. Pittsburgh Steelers | Sunday, September 22nd, 2024 at 1:00pm ET |
| Week 4 | Pittsburgh Steelers vs. Indianapolis Colts | Sunday, September 29th, 2024 at 1:00pm ET |
| Week 5 | Dallas Cowboys vs. Pittsburgh Steelers | Sunday, October 6th, 2024 at 8:20pm ET |
| Week 6 | Pittsburgh Steelers vs. Las Vegas Raiders | Sunday, October 13th, 2024 at 4:05pm ET |
| Week 7 | New York Jets vs. Pittsburgh Steelers | Sunday, October 20th, 2024 at 8:20pm ET |
| Week 8 | New York Giants vs. Pittsburgh Steelers | Monday, October 28th, 2024 at 8:15pm ET |
| Week 9 | Bye Week | |
| Week 10 | Pittsburgh Steelers vs. Washington Commanders | Sunday, November 10th, 2024 at 1:00pm ET |
| Week 11 | Baltimore Ravens vs. Pittsburgh Steelers | Sunday, November 17th, 2024 at 1:00pm ET |
| Week 12 | Pittsburgh Steelers vs. Cleveland Browns | Thursday, November 21st, 2024 at 8:15pm ET |
| Week 13 | Pittsburgh Steelers vs. Cincinnati Bengals | Sunday, December 1st, 2024 at 1:00pm ET |
| Week 14 | Cleveland Browns vs. Pittsburgh Steelers | Sunday, December 8th, 2024 at 1:00pm ET |
| Week 15 | Pittsburgh Steelers vs. Philadelphia Eagles | Sunday, December 15th, 2024 at 4:25pm ET |
| Week 16 | Pittsburgh Steelers vs. Baltimore Ravens | Saturday, December 21st, 2024 at 4:30pm ET |
| Week 17 | Kansas City Chiefs vs. Pittsburgh Steelers | Wednesday, December 25th, 2024 at 1:00pm ET |
| Week 18 | Cincinnati Bengals vs. Pittsburgh Steelers | Sunday, January 5th, 2025 at 1:00pm ET |
