| Week 1 | New England Patriots vs. Cincinnati Bengals | Sunday, September 8th, 2024 at 1:00pm ET |
| Week 2 | Seattle Seahawks vs. New England Patriots | Sunday, September 15th, 2024 at 1:00pm ET |
| Week 3 | New England Patriots vs. New York Jets | Thursday, September 19th, 2024 at 8:15pm ET |
| Week 4 | New England Patriots vs. San Francisco 49ers | Sunday, September 29th, 2024 at 4:05pm ET |
| Week 5 | Miami Dolphins vs. New England Patriots | Sunday, October 6th, 2024 at 1:00pm ET |
| Week 6 | Houston Texans vs. New England Patriots | Sunday, October 13th, 2024 at 1:00pm ET |
| Week 7 | New England Patriots vs. Jacksonville Jaguars | Sunday, October 20th, 2024 at 9:30am ET |
| Week 8 | New York Jets vs. New England Patriots | Sunday, October 27th, 2024 at 1:00pm ET |
| Week 9 | New England Patriots vs. Tennessee Titans | Sunday, November 3rd, 2024 at 1:00pm ET |
| Week 10 | New England Patriots vs. Chicago Bears | Sunday, November 10th, 2024 at 1:00pm ET |
| Week 11 | Los Angeles Rams vs. New England Patriots | Sunday, November 17th, 2024 at 1:00pm ET |
| Week 12 | New England Patriots vs. Miami Dolphins | Sunday, November 24th, 2024 at 1:00pm ET |
| Week 13 | Indianapolis Colts vs. New England Patriots | Sunday, December 1st, 2024 at 1:00pm ET |
| Week 14 | Bye Week | |
| Week 15 | New England Patriots vs. Arizona Cardinals | Sunday, December 15th, 2024 at 4:25pm ET |
| Week 16 | New England Patriots vs. Buffalo Bills | Sunday, December 22nd, 2024 at 1:00pm ET |
| Week 17 | Los Angeles Chargers vs. New England Patriots | Sunday, December 29th, 2024 at 1:00pm ET |
| Week 18 | Buffalo Bills vs. New England Patriots | Sunday, January 5th, 2025 at 1:00pm ET |
