| Week 1 | Baltimore Ravens vs. Kansas City Chiefs | Thursday, September 5th, 2024 at 8:20pm ET |
| Week 2 | Cincinnati Bengals vs. Kansas City Chiefs | Sunday, September 15th, 2024 at 4:25pm ET |
| Week 3 | Kansas City Chiefs vs. Atlanta Falcons | Sunday, September 22nd, 2024 at 8:20pm ET |
| Week 4 | Kansas City Chiefs vs. Los Angeles Chargers | Sunday, September 29th, 2024 at 4:25pm ET |
| Week 5 | New Orleans Saints vs. Kansas City Chiefs | Monday, October 7th, 2024 at 8:15pm ET |
| Week 6 | Bye Week | |
| Week 7 | Kansas City Chiefs vs. San Francisco 49ers | Sunday, October 20th, 2024 at 4:25pm ET |
| Week 8 | Kansas City Chiefs vs. Las Vegas Raiders | Sunday, October 27th, 2024 at 4:25pm ET |
| Week 9 | Tampa Bay Buccaneers vs. Kansas City Chiefs | Monday, November 4th, 2024 at 8:15pm ET |
| Week 10 | Denver Broncos vs. Kansas City Chiefs | Sunday, November 10th, 2024 at 1:00pm ET |
| Week 11 | Kansas City Chiefs vs. Buffalo Bills | Sunday, November 17th, 2024 at 4:25pm ET |
| Week 12 | Kansas City Chiefs vs. Carolina Panthers | Sunday, November 24th, 2024 at 1:00pm ET |
| Week 13 | Las Vegas Raiders vs. Kansas City Chiefs | Friday, November 29th, 2024 at 3:00pm ET |
| Week 14 | Los Angeles Chargers vs. Kansas City Chiefs | Sunday, December 8th, 2024 at 8:20pm ET |
| Week 15 | Kansas City Chiefs vs. Cleveland Browns | Sunday, December 15th, 2024 at 1:00pm ET |
| Week 16 | Houston Texans vs. Kansas City Chiefs | Saturday, December 21st, 2024 at 1:00pm ET |
| Week 17 | Kansas City Chiefs vs. Pittsburgh Steelers | Wednesday, December 25th, 2024 at 1:00pm ET |
| Week 18 | Kansas City Chiefs vs. Denver Broncos | Sunday, January 5th, 2025 at 1:00pm ET |
