New York Giants

Something's gotta give when the Giants face the Raiders this week in a matchup of 2-13 teams. The Giants have the lowest-scoring fantasy defense in the league, but the Raiders have allowed the most fantasy points to opposing defenses this season. After missing Week 15 with shoulder and back injuries, Geno Smith returned to action for the Raiders in Week 16 and promptly threw a first-quarter pick-six against the Texans. Picking a fantasy defense is generally more about the opposing offense than the defense itself, making the Giants an intriguing possibility for Week 17 thanks to the fantastic matchup.