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San Francisco 49ers

San Francisco 49ers

DST - San Francisco 49ers

Week 16 Outlook

SF @ IND
Mon 8:15pm ET
38°
Matchup (?)
Week Rank (ECR) DST #11
Projection 5.2 pts

Roster %

 
Yahoo
48%
 
ESPN
42%
 
FanDuel
 
DraftKings

Availability



49ers D/ST allows 24 points in Week 15 win

The 49ers D/ST allowed 24 points while failing to notch a sack or record a turnover in a 37-24 win over the Titans in Week 15.

Fantasy Impact

San Francisco emerged victorious while holding the Titans to 306 yards of total offense in the win. They will now prepare to take on the Colts in Week 16.

Matthew AdamDec 15, 2025
49ers D/ST dominates Sunday

The 49ers defense allowed eight points on 253 total yards with three sacks and two fumble recoveries on Sunday.

Fantasy Impact

Besides a late touchdown in the first half, it was a dominant effort by San Francisco against Shedeur Sanders and Cleveland. They are on their bye next week, but hold some streaming appeal in Week 15 against the Titans.

Ari Koslow2 weeks ago
49ers D/ST plays well in win Monday

The 49ers' D/ST logged two interceptions and one sack while allowing nine points in Monday night's win over the Carolina Panthers.

Fantasy Impact

San Francisco's defense took advantage of a positive matchup on Monday night. They held the Panthers to just nine points and were able to log several big plays to help out the offense. They have a great schedule coming up with their next two games being against the Browns and the Titans respectively.

Leo Sells3 weeks ago
San Francisco 49ers D/ST holds Arizona to 22 points

The San Francisco 49ers D/ST picked off Cardinals' QB Jacoby Brissett twice in the team's 41-22 win over Arizona and recovered a fumble. They failed to record a sack.

Fantasy Impact

The 49ers defense somehow gave up 488 yards of offense in this game but only 22 points. Part of that was no doubt Arizona repeatedly shooting themselves in the foot with a total of 17 penalties called against them in this game, as well as three turnovers. With the Niners having little in terms of a pass rush, they are a scary bet for a streaming defense most weeks, and are best left on waivers unless the matchup is just too good to pass up.

Garrett Ball4 weeks ago
49ers D/ST allows 42 points in Week 10 loss

The 49ers D/ST allowed 280 passing yards, 126 rushing yards, and 42 points in their 42-26 loss to the Rams.

Fantasy Impact

The 49ers' defense tallied one sack and failed to force a turnover in a lopsided loss to the Rams. The Rams' offense was able to move the ball effectively against an injury depleted 49ers' defense. The team will look to bounce back in Week 11 when they head to Arizona for a divisional matchup with the Cardinals.

Jesse Garcia5 weeks ago