49ers pass-rusher Nick Bosa (hip, oblique) has been ruled out for Sunday's matchup vs. the Packers. (Source: Cam Inman on Twitter)
Fantasy Impact: Bosa was a DNP in practice all week after injuring his hip/oblique area vs. the Seahawks in Week 11. His next chance to play will come in Week 13 vs. the Bills.
49ers QB Brock Purdy has been ruled out for Sunday's game vs. the Packers with a shoulder injury. Brandon Allen will get the start. (Source: Ian Rapoport on Twitter)
Fantasy Impact: Purdy picked up a right shoulder injury in last week's game against the Seahawks, limiting his participation in practice this week. He will sit Week 12 out, with his next chance to play coming in Week 13 vs. the Bills.
49ers OL Trent Williams (ankle) was not seen during the open portion of practice Friday. (Source: Nick Wagoner on Twitter )
Fantasy Impact: Williams has not practiced at all this week, leaving his status for Sunday in doubt. The 49ers will provide injury designations for Week 12 soon.
49ers RB Christian McCaffrey (Achilles) was a limited participant in practice Thursday. (Source: Nick Wagoner on Twitter )
Fantasy Impact: McCaffrey is expected to miss practice time as the team continues to manage his Achilles injury. There should be no concern that he misses the 49ers' Week 12 matchup against Green Bay.
49ers TE George Kittle (hamstring) was a limited participant in practice Thursday. (Source: Nick Wagoner on Twitter )
Fantasy Impact: Kittle has logged limited practice time in both sessions to open the week. It is expected that he will return against Green Bay after missing Week 11.
49ers GM John Lynch said "we're getting closer" to having Dre Greenlaw coming back. (Source: Matt Barrows on Twitter)
Fantasy Impact: Lynch added that once Greenlaw's practice window opens, he will use a good chunk of that window. He is likely still at least a few weeks away from officially returning for San Francisco.
Yetur Gross-Matos is on track to return on Sunday against the Seahawks. (Source: David Lombardi on Twitter)
Fantasy Impact: It's "looking pretty good" according to 49ers GM John Lynch. Gross-Matos has been sidelined for the past month after undergoing surgery on his knee.
49ers WR Jauan Jennings (ankle) was a limited participant in practice Thursday. (Source: Nick Wagoner on Twitter )
Fantasy Impact: Jennings was midweek addition to the injury report, meaning he likely picked up the injury during practice. He will have one more session to avoid an injury designation ahead of Sunday's matchup with Seattle.
Sun, Nov 10th 11:44am EST
By Josh Collier
49ers WR Deebo Samuel Sr. (rib, oblique) is officially active for Week 10. (Source: San Francisco 49ers on Twitter)
Fantasy Impact: Samuel was a limited participant in practice all week and listed as questionable headed into this weekend, but will get the green light for Sunday's matchup vs. the Buccaneers.
Jake Moody (ankle) was officially limited at San Francisco's practice on Wednesday. (Source: Matt Barrows on Twitter)
Fantasy Impact: Moody will be a limited participant at San Francisco's first practice of the week due to an ankle injury. It remains to be seen whether or not he will be available to play in Week 10, and if he's active, fantasy managers should expect him to be an above-average fantasy option at the kicker position.
Mon, Oct 28th 12:57pm EDT
By Ari Koslow
49ers coach Kyle Shanahan said Jordan Mason “maybe” could have returned to Sunday's game against the Cowboys. (Source: Lindsey Thiry on Twitter)
Fantasy Impact: Mason left in the 2nd quarter during Sunday's game against Dallas. He was dealing with an AC joint sprain that a couple of weeks ago and is now dealing with another shoulder injury. As of now, Christian McCaffrey is "on pace" to return in Week 10 after the 49ers bye week.
George Odum has been listed as questionable for Sunday's game against the Cowboys. (Source: Josh Dubow on Twitter)
Fantasy Impact: Odum was limited at practice on Thursday and Friday. He should be on the favorable side of questionable heading into Sunday.
Deommodore Lenoir has been listed as questionable for Sunday's game against the Cowboys. (Source: Josh Dubow on Twitter)
Fantasy Impact: Lenoir was limited to close the week on Friday. He should be good to go for Sunday's game barring any setbacks with his illness.
Kevin Givens has been ruled out for Sunday's game against the Cowboys. (Source: Josh Dubow on Twitter)
Fantasy Impact: Givens was absent from practice all week for the 49ers. He'll be sidelined on Sunday.
Brandon Aiyuk (knee) has officially been placed on injured reserve and will miss the remainder of the season. (Source: Adam Schefter on Twitter)
Fantasy Impact: Aiyuk recently suffered a torn ACL and MCL, which will knock him out for the remainder of the season. The team officially placed him on injured reserve on Wednesday, which will open up a roster spot for them. Jauan Jennings and rookie Ricky Pearsall are both prime candidates to see increased work in his absence.
The 49ers are placing K Matthew Wright on injured reserve. (Source: Adam Schefter on Twitter)
Fantasy Impact: Wright had an MRI return negative last week, but it was not enough for him to avoid the IR. He will miss at least the next four games.
San Francisco 49ers WR Ricky Pearsall will make his NFL debut in Week 7 against the Kansas City Chiefs. (Source: Adam Schefter on Twitter)
Fantasy Impact: The rookie WR missed the beginning of his rookie campaign after an unfortunate incident where he was shot in the chest during an attempted robbery. Pearsall was set to miss at least the first four games but took a little bit longer due to his recovery. Now, the shifty, creative wideout is set to make his NFL debut. And with WR Jauan Jennings out with a hip injury, he can serve as the WR3 behind Deebo Samuel Sr. and Brandon Aiyuk.
49ers CB Charvarius Ward (knee) is officially inactive for Thursday’s game with Seattle.
Fantasy Impact: Ward will miss Week 6 after suffering a knee injury during Week 5. With a short week, the news of Ward being inactive is not a surprise. He will have the extra time to rest and rehab his injured knee.
49ers LB Fred Warner (ankle) was a full participant in practice Wednesday. (Source: Ian Rapoport on Twitter )
Fantasy Impact: Warner will head into Thursday's matchup with Seattle without an injury designation. He will suit up, providing the 49ers with a key component of their defense.
The 49ers have placed S Talanoa Hufanga on injured reserve. (Source: 49ers on Twitter )
Fantasy Impact: Hufanga tore ligaments in his wrist and will now be forced to miss at least a month, per head coach Kyle Shanahan. George Odum is expected to step in until Hufanga returns.
