NFL Week 16 Player Prop Bets, Odds & Picks

At our sports betting website, BettingPros, we compiled several projection sources to come up with consensus projections. We then compared these projections to the prop bet odds from the sportsbooks to give you the best prop bet picks. View the best player prop bets for this week’s slate with our NFL Prop Bet Cheat Sheet. Here are our top NFL player prop bet picks for this week’s action.

NFL Player Prop Bets, Odds, Picks & Predictions

What is Betting Against the Spread?

Betting “against the spread” refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.


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Whether you’re new to sports betting or a betting pro, our Sports Betting Strategy and Advice page is for you. You can get started with our 101 section — including 10 Sports Betting Tips for Beginners — or head to more advanced strategy — like Key Numbers When Betting Against the Spread — to learn more.