Looking to dominate your Week 16 PrizePicks entries? FantasyPros expert Andrew Erickson is here to help. In this week’s Fantasy Football Forecast, Erickson dives into the matchups, stats, and trends to deliver his top PrizePicks player predictions. Whether you’re aiming to cash in on the hottest player lines or identify sneaky value plays, Erickson’s insights are your ticket to success. Let’s break down his top picks and find the edge you need to win big this week.
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Week 16’s Best PrizePicks NFL Player Predictions
Matthew Stafford MORE THAN 244.5 Passing Yards
With Nacua and Kupp healthy this season, Stafford has tossed for at least 250.5 passing yards in seven of his nine starts. Take the MORE than on PrizePicks for Week 16, with his passing yards prop set at 244.5 passing yards.
Deebo Samuel LESS THAN 47.5 Receiving Yards
Samuel has been beyond terrible for fantasy football purposes, and that was on full display Thursday night. At this point in the year, no kind of usage is going to change his production. He has had opportunities to deliver and has fallen well short of expectations. Take the LESS than on his receiving line on Prizepicks. It’s set at 47.5 yards. He hasn’t had more than 22 yards in five straight games.
Jayden Daniels LESS THAN 223.5 Passing Yards
Jayden Daniels completed 25 of 31 passes for 226 yards, two touchdowns, and 0 interceptions, achieving a stellar passer rating of 118.5. Daniels delivered a composed and accurate performance, leading multiple scoring drives. The rookie QB displayed his dual-threat ability with 11 carries for 66 yards (6.0 YPC), including a 24-yard run. However, the matchup coming up versus the Eagles is going to be rough. No QB has hit their closing line passing yards prop versus the Eagles since their bye week. Daniels passed for just 191 yards when these teams last played. Take the LESS THAN on Daniels’ 223.5 passing yards projection on Prizepicks for Week 16. The projections have him under 200 passing yards.
Dalton Kincaid MORE THAN 36.5 Receiving Yards
Dalton Kincaid caught four passes for 53 yards in Week 15. Kincaid led the team in receiving air yards with 84 yards (24% air yard share) and a target share of 22%, catching four passes for 53 yards. He was the most targeted player in the game, with eight targets. He caught a 10-yard TD that was called back on an offensive holding call. He was the biggest winner among the Bills’ skill position players, being targeted on 38% of his routes run. Even with a limited role, I’d expect his routes/snaps to increase another week back from his injury. I think his Prizepicks line is way too low at 36.5 yards for Week 16. Take the MORE THAN. Projections have him well OVER 40 receiving yards.
Jared Goff LESS THAN 258.5 Passing Yards
The Lions’ passing game ROS doesn’t have the same soft schedule. For the rest of the season, their quarterbacks have the 32nd-ranked schedule. I think a sneaky “landmine” move might be to drop Goff ahead of this outdoor matchup versus the Bears. Therefore, I am going LESS THAN on Goff’s 258.5 passing yards projection on Prizepicks this week. He is 50% at this number in all his road games this season. He failed to hit over 222 yards the last time he played the Bears at home. In his lone game outdoors this season, he passed for under 150 yards. The projections have him well below 240 passing yards.
Bo Nix MORE THAN 17.5 Rushing Yards
I like Nix’s chances of running a lot against the Chargers in Week 16. He rushed for 60-plus yards against them earlier this season, and the Chargers have allowed a ton of yardage to opposing QBs. Entering Week 15, the Chargers had allowed the 4th-most rushing yards over expected (+68), 6th-most yards per carry (9.1), and tied for the 2nd-most first downs (16) against scrambles this season (Next Gen Stats). Baker Mayfield rushed for 25 yards on two carries in Week 16 versus the Bolts. Take the MORE THAN 17.5 rushing yards for Nix on Prizepicks this week for Thursday Night Football.