Tonight’s MLB DFS main slate at DraftKings and FanDuel starts at 6:40 p.m. ET. However, there are 10 games on DK’s main slate and only eight on FD’s. The latter platform doesn’t have the last two MLB games of the night on the main slate. And, of course, gamers can also make pick ’em choices at Underdog.
Check out our best picks on the MLB Underdog Cheat Sheet 
Today’s MLB DFS & Player Props Picks
Wednesday’s Starting Pitcher Rankings
Tyler Glasnow (LAD) vs. ARI
According to FanGraphs, Tyler Glasnow's 2.56 xERA this season is the lowest among tonight's probable starters. He's in excellent form, too. In his past five starts spanning 33.0 innings, Glasnow has had a 2.18 ERA, 2.08 SIERA, 0.85 WHIP, 5.6 BB%, 37.6 K%, 29.4 CSW%, 114 Stuff+, 103 Location+ and 109 Pitching+.
He has an average-to-good matchup and tasty betting info. This year, the Diamondbacks are 25th in wRC+ (92) with a 21.1 K% versus righties and tied for 13th in wRC+ (99) with a 22.0 K% on the road. They were also 16th in wRC+ (98) and had a 23.4 K% in the previous 14 days. Additionally, the Dodgers are -275, and the game's total is 8.0 runs.
Ryan Pepiot (TB) vs. BOS
Ryan Pepiot will return from the Injured List (IL) tonight. He isn't returning from an arm injury, so he can hopefully avoid any significant pitch restriction tonight. In his first seven starts spanning 36.2 innings this season, Pepiot had a 3.68 ERA, 2.94 xERA, 3.34 SIERA, 0.93 WHIP, 7.8 BB%, 29.1 K%, 29.9 CSW%, 117 Stuff+, 100 Location+ and 106 Pitching+.
The Red Sox have a semi-potent but strikeout-prone offense. This season, they have a 24.3 K% versus righties and a 25.4 K% on the road. In the last 14 days, they were tied for 20th in wRC+ (92) with a 24.7 K%. The Tampa Bay is -120, and the game's total is 7.5 runs. Pepiot is the top SP2 in all game types on DK and my favorite pitching option on FD's Dodgers-less slate.
Jesus Luzardo (MIA) vs. MIL
Jesus Luzardo is strictly a GPP choice. Still, he has an appealing ceiling. In two starts totaling 11.2 innings since returning from the IL, Luzardo has had a 1.54 ERA, 2.09 SIERA, 0.86 WHIP, 2.3 BB%, 34.1 K%, 31.5 CSW%, 93 Stuff+, 101 Location+ and 104 Pitching+.
The lefty is also sharp at home. In 24 home starts spanning 135.1 innings since last year, Luzardo has had a 3.19 ERA, 3.57 xFIP, 1.09 WHIP, 7.5 BB% and 29.4 K%. The Brewers have a potent lineup. Yet, they're tied for 17th in wRC+ (99) and have a 25.0 K% against lefties in 2024. Finally, the Marlins are slight underdogs (+115), but the game's total is a pitcher-friendly 7.5 runs.
Suggested Lineup Stacks
The Dodgers are available to stack only on DK, and they're a dreamy stack there. LA is second in wRC+ (122) against righties this season and second (130 wRC+) at home. Their projected lineup also has seven players with at least a 103 wRC+ against righties since 2021, and four have had at least a 124 wRC+. The matchup is great, too. In Ryne Nelson's past three starts, he's had a 9.88 ERA, 4.05 SIERA, 2.27 WHIP and allowed 1.32 HR/9.
- Home (Tropicana Field)
- Game Total/Moneyline: 7.5 Runs/TB -120
The Rays have an average matchup at home tonight. Brayan Bello has a 3.96 ERA, 4.31 xERA and 3.71 SIERA in seven starts this year. Yet, the righty has also ceded an eye-catching 1.98 HR/9. The Rays have excelled at home this year, tying for 10th in wRC+ (109). Tampa Bay's projected lineup also has six players with at least a 118 wRC+ against righties since 2021.
Core Studs
- In 53 plate appearances this season, Josh Lowe has a .302 OBP, .204 ISO and 113 wRC+. Conversely, Bello has allowed lefties a .354 wOBA.
- Since 2021, Shohei Ohtani has had a .402 OBP, .324 ISO and 173 wRC+ against righties.
- Marcell Ozuna is a fine pick on DK, but he's here with FD in mind. The slugger is nuking baseballs this year, sporting a .405 OBP, .307 ISO and 189 wRC+ with 14 homers in 190 plate appearances.
Value Plays/Punts
- In 134 plate appearances this year, Joey Ortiz has a .391 OBP, .232 ISO and 158 wRC+.
- Jonathan Aranda conquered the minors and is getting a crack at regular playing time for the Rays. His batted-ball data is much more impressive than his actual stats this season.
- In 181 plate appearances in Triple-A this season, Miguel Vargas has hit eight homers and stolen eight bases with a .436 OBP, .288 ISO and 150 wRC+. Can his success translate to the majors? It remains to be seen, but his salary is palatable as a punt against a pitcher allowing a .469 wOBA to righties this season.
Wednesday's Top 3 Underdog Fantasy Player Props
Check out our best picks on the MLB Underdog Cheat Sheet
Shohei Ohtani: 9.5 Fantasy Points - Higher
Ohtani is on another level this season. In 222 plate appearances this year, Ohtani has hit 13 homers and stolen 13 bases with a .425 OBP, .350 ISO and 205 wRC+. He can smash in a cushy matchup tonight.
Marcell Ozuna: 1.5 Total Bases - Higher
Ozuna is another holdover from the core studs. In 385 plate appearances against lefties since 2021, he's hit 15 doubles and 18 homers with a .246 batting average, .444 slugging and .198 ISO. Conversely, Justin Steele has allowed six doubles, four homers, a .291 batting average and .618 slugging to 63 righties this year.
Austin Gomber has snuck over 4.5 strikeouts in back-to-back games, striking out precisely five batters in those games. However, the veteran lefty has struck out fewer than 4.5 batters in six of nine starts this season. In nine starts spanning 50.2 innings this year, Gomber has struck out 35 batters at 6.22 K/9 and with a 16.9 K% and 27.5 CSW%. Gomber isn't a strikeout whiz and has a challenging matchup for strikeouts tonight. This year, the Diamondbacks have the third-lowest strikeout rate (18.2 K%) against lefties. Arizona is also tied for the third-lowest strikeout rate (18.4 K%) at home.
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Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.
