Matthew Freedman’s Fantasy Football Week 6 Rankings & Start/Sit Lineup Advice (2022)

Here are my fantasy football rankings for Week 6. You can find our expert consensus fantasy football rankings for the week here. And you can also sync your fantasy football league for free using our My Playbook tool for custom advice, rankings, and analysis. You can check out all of my favorite players of the week here.

• Pat Fitzmaurice’s Weekly Rankings
• Andrew Erickson’s Weekly Rankings
• Derek Brown’s Weekly Rankings
• Joe Pisapia’s Weekly Rankings

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Fantasy Football Week 6 Rankings

Kirk Cousins (MIN) at MIA: Vikings -3 | 45.5 O/U

• Cousins has league-high marks with 62 attempts of 10-plus yards downfield and 21 pass attempts inside the 10-yard line (per our Advanced QB Stats Report and Red Zone Stats Report).
• The Dolphins might be without Nos. 1-2 CBs Xavien Howard (groin) and Byron Jones (ankle, PUP) and are No. 32 in defensive pass DVOA (31.9%, per Football Outsiders).

Geno Smith (SEA) vs. ARI: Seahawks +2.5 | 51 O/U

• Smith is No. 1 in completion percentage (75.2%), No. 2 in AY/A (8.9), and No. 3 in composite EPA + CPOE (0.189) — just as we all expected before the season started.
• The Cardinals’ defense is No. 32 in dropback SR (53.3%).
• Seahawks HC Pete Carroll is 16-8 ATS as a home underdog.

Jimmy Garoppolo (SF) at ATL: 49ers -5.5 | 44.5 O/U

• Since joining the 49ers in 2017, Garoppolo is No. 5 in composite EPA + CPOE (0.137) — behind only Patrick Mahomes (0.177), Drew Brees (0.166), Deshaun Watson (0.144) and Aaron Rodgers (0.138).
• The Falcons’ defense is No. 31 in dropback SR (53.0%): Garoppolo has literally a five-star matchup.
• For his career, Garoppolo is 21-9 ATS on the road.

Daniel Jones (NYG) vs. BAL: Giants +5 | 45 O/U

• Jones is very much #NotGood (6.2 AY/A this year, 6.3 AY/A for career), but he could have a pass-heavy game script as a big road underdog (+190 at DraftKings).
• The Ravens will be without CB Kyler Fuller (knee, IR) and FS Marcus Williams (wrist, IR) and are No. 2 in most fantasy points allowed to opposing quarterbacks (23.6 FPPG).
• Jones is — somehow — 12-4 ATS as a road underdog.

Justin Fields (CHI) vs. WAS: Bears -1 | 38 O/U

• Over the past two weeks, Fields has 382 yards, one touchdown, and no interceptions on 43 pass attempts — and that sounds horrible — but that’s at least an improvement on what he did in Weeks 1-3 (297-2-4 passing on 45 attempts).
• Fields is No. 3 in quarterback rush attempts (42) behind only Jalen Hurts (68) and Lamar Jackson (49, per our Fantasy Football Stats Report).
• The Commanders are No. 29 in defensive pass DVOA (20.6%).

Running Backs

Melvin Gordon (DEN) at LAC: Broncos +5 | 45.5 O/U

• Last week, Gordon had a season-high 103 yards on 15 carries and three targets in the absence of No. 1 RB Javonte Williams (knee, IR), who is out for the year.
• Coming off of Thursday Night Football and playing on Monday, the 29-year-old veteran should benefit from the four extra days of rest.
• The Chargers are No. 1 in most fantasy points allowed to opposing backfields (28.9 FPPG).

Kareem Hunt (CLE) vs. NE: Browns -3 | 42.5 O/U

• Even with No. 1 RB Nick Chubb dominating opponents, Hunt in every game has managed to earn 10-plus carries and 2-4 targets, which he has leveraged into 330 yards and three touchdowns.
• The Patriots’ defense is No. 30 in rush SR (50.0%).

Raheem Mostert (MIA) vs. MIN: Dolphins +3 | 45.5 O/U

• After opening the season in a committee with RB Chase Edmonds, the 30-year-old Mostert took control of the Dolphins backfield in Weeks 4-5 with a 70% snap rate, which he turned into 33-182-1 rushing and 3-21-0 receiving on six targets.
• In his 20 career games with 12-plus opportunities, Mostert has 15.0 FPPG.
• Mostert could seemingly get injured at any moment — but he has looked good this season with the Dolphins.

Eno Benjamin (ARI) at SEA: Cardinals -2.5 | 51 O/U

• No. 1 RB James Conner (ribs), No. 2 RB Darrel Williams (knee), and No. 4 RB Jonathan Ward (hamstring) all exited Week 5 early with injuries and are uncertain for Week 6.
• Amidst last week’s carnage, Benjamin had a serviceable eight carries and four targets and would be in line for more usage if both Conner and Williams were out.
• The Seahawks are No. 5 in most fantasy points allowed to opposing backfields (25.6 FPPG).

Wide Receivers

D.J. Moore (CAR) at LAR: Panthers +10.5 | 40.5 O/U

• What if the “loss” of HC Matt Rhule (terminated) and QB Baker Mayfield (ankle, likely out) is addition by subtraction?
• After getting six targets in each of Weeks 1-3, Moore has 19 targets (and two carries) over the past two weeks.
• Even with No. 1 CB Jalen Ramsey, the Rams are No. 5 in most fantasy points allowed to opposing wide receivers (34.5 FPPG), and they could be without Nos. 2-4 CBs Troy Hill (groin, IR), David Long (groin), and Cobie Durant (hamstring).

Tyler Boyd (CIN) at NO: Bengals -1.5 | 43.5 O/U

• No. 2 WR Tee Higgins (ankle) “played” through an injury last week, but he saw just 10 snaps with no targets, and his status is uncertain for Week 6.
• In his four entire or partial games without Higgins since last year, Boyd has a respectable 20-219-2 receiving on 28 targets.
• The Saints are No. 29 in defensive DVOA against supplementary wide receivers (37.1%).

Darnell Mooney (CHI) vs. WAS: Bears -1 | 38 O/U

• The Bears are last in the league with a 39.9% pass-play rate, but at least Mooney is still No. 1 on the team in targets (21), receptions (10), and yards receiving (173).
• The Commanders benched No. 1 CB William Jackson last week for poor performance and are No. 4 in most fantasy points allowed to opposing wide receivers (35.2 FPPG).

Rondale Moore (ARI) at SEA: Cardinals -2.5 | 51 O/U

• Since making his 2022 debut in Week 4, Moore has played an 88% snap rate and been the No. 2 wide receiver with 13 targets for 10-79-0 receiving (and three carries … for -11 yards, ugh).
• The Seahawks are No. 28 in defensive pass DVOA against No. 2 wide receivers (35.2%).

K.J. Hamler (DEN) at LAC: Broncos +5 | 45.5 O/U

• The Chargers are No. 28 in defensive DVOA against supplementary wide receivers (36.6%).
• Let’s just say that QB Russell Wilson owes Hamler some targets …

Tight Ends

Evan Engram (JAX) at IND: Jaguars +2 | 42 O/U

• Engram had a nice 6-69-0 receiving on 10 targets last week, and for the season he has basically functioned as another wide receiver for the team, ranking No. 3 in pass play snaps (171), routes run (155), and receptions (19).
• Against the Colts in Week, 2, Engram had 7-46-0 receiving on eight targets.
• The Colts are No. 5 in most fantasy points allowed to tight ends (13.5 FPPG).

Taysom Hill (NO) vs. CIN: Saints +1.5 | 43.5 O/U

• Hill isn’t a traditional tight end — he has just 14 routes and one target on the year — but he gets regular usage each game as a wildcat quarterback, and as such he has 21-228-5 rushing and a 22-yard touchdown passing.
• Hill leads the Saints with four carries inside the 20-yard line and three carries inside the 10 — all of which he has converted into touchdowns.
• Especially in the bye weeks, Hill’s upside is too great to ignore.

Hayden Hurst (CIN) at NO: Bengals -1.5 | 43.5 O/U

• No. 2 WR Tee Higgins (ankle) is uncertain, and Hurst’s two biggest games this year (Weeks 1 & 5, 11-99-1 receiving on 15 targets) have been when Higgins has played less than 30% of the snaps.
• The Saints will be without S P.J. Williams (quadriceps, IR) and maybe also S Marcus Maye (ribs), who hasn’t played since Week 2.

If you want to dive deeper into fantasy football, be sure to check out our award-winning slate of Fantasy Football Tools as you navigate your season. From our Start/Sit Assistant – which provides your optimal lineup, based on accurate consensus projections – to our Waiver Wire Assistant – which allows you to quickly see which available players will improve your team and by how much – we’ve got you covered this fantasy football season.