The opening contest of the 2022 NFL season has a championship fight feel, with a pair of heavyweights doing battle. The defending Super Bowl champion Rams host the 2022 Super Bowl champion betting favorite Bills. The spread for the game is small, the total is north of 50, and there’s elite talent on both sides of the ball for the well-rounded squads. Below, find out the players gamers should mix into their showdown lineups.
Beyond our daily fantasy football content, be sure to check out our Daily Fantasy Football Tools. From our Lineup Optimizer – which allows you to build winning DFS lineups in seconds for Cash and GPP contests – to our DFS Cheat Sheets – that helps you get a quick read on the day’s players – we’ve got you covered this fantasy football season.
