Andrew Luck was inactive Sunday due to a shoulder injury

Two big-name quarterbacks dealt with injuries this week, with one inactive and one putting up big numbers. Hamstring injuries continue to plague offensive performers and Dallas might not have any healthy payers left soon. Here is a quick recap of some key injuries that happened in Week 4.

Import your team for free to get lineup advice

• Drew Brees (NO QB) was able to play in Week 4 but looked average for most of the game against the Cowboys. His stats appear great simply because of the 80-yard touchdown pass to C.J. Spiller on the opening drive of overtime. For much of the game, Brees’ average completion was just 6.3 yards per pass attempt and it appears as if he will require a great deal of volume to compile his stats. Don’t cut bait on him yet but, if his shoulder continues to bother him, you might need a solid second quarterback on your fantasy roster.

• Lance Dunbar (Dal RB) was injured on the opening kickoff of the second half of yesterday’s game against New Orleans and did not return to action. He is scheduled to have an MRI on Monday but Dallas fears he has a torn ACL and MCL in his left knee, which would put him out of action for the rest of the season.

• Malcolm Floyd (SD WR) left yesterday’s game against Cleveland when he sustained a concussion after making a 20-yard reception. The scary part about this is that he returned to the contest before he was removed and ultimately diagnosed with a concussion.

• Steve Johnson (SD WR) suffered a non-contact hamstring injury in Sunday’s game against Cleveland. While it did appear he wanted to return to the game, San Diego ultimately held him out of action. With both Johnson and Malcolm Floyd injured, look for increased targets for WR Keenan Allen, RB Danny Woodhead, and TE Antonio Gates, who is returning from a suspension.

• Andrew Luck (IND QB) missed the first game of his career this weekend because of a right shoulder injury, with an MRI showing a contusion. “We worked him out Saturday morning, and we were hopeful he could come in [Sunday] morning, we were going to evaluate him and see how he felt and he just wasn’t ready,” Colts coach Chuck Pagano said. “Didn’t have the arm strength and all that stuff.” The Colts have a short week, playing this week’s Thursday night game. Though the Colts plan on him being available Thursday night any setback could change those plans. If you own Luck monitor his progress right up until your roster lock on Thursday.

• Marshawn Lynch (SEA RB) will miss his first game since 2011, sitting out Monday night’s contest because of his hamstring injury. Initially, Lynch’s status was supposed to be a game-time decision. Since Seattle announced it early I am a bit concerned about his status heading into Week 5. If you didn’t protect yourself against Lynch’s loss this week don’t make that mistake again. Look to add Thomas Rawls as Lynch’s handcuff for the rest of the season, as hamstring issues can be tricky.

• LeSean McCoy (BUF RB) was already inactive heading into Week 4 but, with an MRI revealing a new strain in his injured hamstring. It is expected to take three-four weeks before he is at full strength, which appears to be his goal. “One thing I just promised myself is I can’t go out there if I’m not 100 percent,” McCoy said. “Whatever it is, I’m rushing to get back, but I’m not playing until I’m 100 percent.” Buffalo struggled to run the ball against the Giants on Sunday, but look for rookie Karlos Williams to continue to get the bulk of the carries for the Bills.

• Cecil Shorts (HOU WR) injured his left shoulder during Sunday’s loss to the Falcons. Two things about this injury bother me. First, Shorts is a fellow Mount Union alum, so I am frustrated on a personal level. Second, this injury occurred on the last play of the game in a blowout loss which, as an athletic trainer, always bothers me. Shorts could miss anywhere from one to three months, depending on the associated structural damage found after he has an MRI. Also look for Arian Foster to get more touches this week, increasing his fantasy value.

• Nate Washington (HOU WR) injured his hamstring and did not return to Sunday’s contest. With both Washington and Cecil Shorts question marks heading into Thursday’s game against Indianapolis, look for DeAndre Hopkins to get plenty of targets.

Get Start/Sit & Waiver Advice with My Playbook

Jeremy Tiermini is a correspondent at FantasyPros. To read more from Jeremy follow him @JeremyTiermini.